May 17, 2025

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Health effects associated with exposure of children to physical violence, psychological violence and neglect: a Burden of Proof study

Health effects associated with exposure of children to physical violence, psychological violence and neglect: a Burden of Proof study
  • Global Status Report on Preventing Violence against Children 2020 (United Nations Children’s Fund, 2020); https://hdl.handle.net/20.500.14041/3498

  • Hillis, S., Mercy, J., Amobi, A. & Kress, H. Global prevalence of past-year violence against children: a systematic review and minimum estimates. Pediatrics 137, e20154079 (2016).

    Article 
    PubMed 

    Google Scholar 

  • A Familiar Face: Violence in the Lives of Children and Adolescents (United Nations Children’s Fund, 2017).

  • Devries, K. et al. Who perpetrates violence against children? A systematic analysis of age-specific and sex-specific data. BMJ Paediatr. Open 2, e000180 (2018).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Stöckl, H., Dekel, B., Morris-Gehring, A., Watts, C. & Abrahams, N. Child homicide perpetrators worldwide: a systematic review. BMJ Paediatr. Open 1, e000112 (2017).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Garwood, S. K., Gerassi, L., Jonson-Reid, M., Plax, K. & Drake, B. More than poverty: the effect of child abuse and neglect on teen pregnancy risk. J. Adolesc. Health 57, 164–168 (2015).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Fortin-Langelier, E. et al. A matched cohort study of the association between childhood sexual abuse and teenage pregnancy. J. Adolesc. Health 65, 384–389 (2019).

    Article 
    PubMed 

    Google Scholar 

  • Hughes, K. et al. Health and financial costs of adverse childhood experiences in 28 European countries: a systematic review and meta-analysis. Lancet Public Health 6, e848–e857 (2021).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Baldwin, J. R. et al. Childhood maltreatment and mental health problems: a systematic review and meta-analysis of quasi-experimental studies. Am. J. Psychiatry 180, 117–126 (2023).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Spencer, C. N. et al. Health effects associated with exposure to intimate partner violence against women and childhood sexual abuse: a Burden of Proof study. Nat. Med. 29, 3243–3258 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Chandan, J. S. et al. Increased cardiometabolic and mortality risk following childhood maltreatment in the United Kingdom. J. Am. Heart Assoc. 9, e015855 (2020).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Bhutta, Z. A., Bhavnani, S., Betancourt, T. S., Tomlinson, M. & Patel, V. Adverse childhood experiences and lifelong health. Nat. Med. 29, 1639–1648 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Berens, A. E., Jensen, S. K. G. & Nelson, C. A. Biological embedding of childhood adversity: from physiological mechanisms to clinical implications. BMC Med. 15, 135 (2017).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Liu, R. T., Scopelliti, K. M., Pittman, S. K. & Zamora, A. S. Childhood maltreatment and non-suicidal self-injury: a systematic review and meta-analysis. Lancet Psychiatry 5, 51–64 (2018).

    Article 
    PubMed 

    Google Scholar 

  • Caslini, M. et al. Disentangling the association between child abuse and eating disorders: a systematic review and meta-analysis. Psychosom. Med. 78, 79–90 (2016).

    Article 
    PubMed 

    Google Scholar 

  • Ménard, A. D. & MacIntosh, H. B. Childhood sexual abuse and adult sexual risk behavior: a review and critique. J. Child Sex. Abuse 30, 298–331 (2021).

    Article 

    Google Scholar 

  • Halpern, S. C. et al. Child maltreatment and illicit substance abuse: a systematic review and meta‐analysis of longitudinal studies. Child Abuse Rev. 27, 344–360 (2018).

    Article 

    Google Scholar 

  • Fry, D. et al. The relationships between violence in childhood and educational outcomes: a global systematic review and meta-analysis. Child Abuse Negl. 75, 6–28 (2018).

    Article 
    PubMed 

    Google Scholar 

  • Thielen, F. W. et al. Long-term economic consequences of child maltreatment: a population-based study. Eur. Child Adolesc. Psychiatry 25, 1297–1305 (2016).

    Article 
    PubMed 

    Google Scholar 

  • Pearson, I. et al. The co-occurrence of intimate partner violence and violence against children: a systematic review on associated factors in low- and middle-income countries. Trauma Violence Abuse 24, 2097–2114 (2023).

    Article 
    PubMed 

    Google Scholar 

  • Bordignon, E. et al. Child maltreatment associates with violent victimization in young adulthood: a Brazilian birth cohort study. BMC Public Health 23, 2287 (2023).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Hidden in Plain Sight (United Nations Children’s Fund, 2014); (2014).

  • Peterman, A. et al. Ethical reporting of research on violence against women and children: a review of current practice and recommendations for future guidelines. BMJ Glob. Health 8, e011882 (2023).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • GBD 2021 Risk Factors Collaborators. Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet 403, 2162–2203 (2024).

    Article 

    Google Scholar 

  • Dalechek, D. E., Caes, L., McIntosh, G. & Whittaker, A. C. Anxiety, history of childhood adversity, and experiencing chronic pain in adulthood: a systematic literature review and meta-analysis. Eur. J. Pain 28, 867–885 (2024).

    Article 
    PubMed 

    Google Scholar 

  • Zhu, J., Racine, N., Devereux, C., Hodgins, D. C. & Madigan, S. Associations between adverse childhood experiences and substance use: a meta-analysis. Child Abuse Negl. 7, 106431 (2023).

    Article 

    Google Scholar 

  • Ding, W., Xu, Y., Kondracki, A. J. & Sun, Y. Childhood adversity and accelerated reproductive events: a systematic review and meta-analysis. Am. J. Obstet. Gynecol. 230, 315–329 (2024).

    Article 
    PubMed 

    Google Scholar 

  • Jonas, L. et al. A systematic review and meta-analysis investigating the impact of childhood adversities on the mental health of LGBT+ youth. JCPP Adv. 2, e12079 (2022).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Zheng, P. et al. The Burden of Proof studies: assessing the evidence of risk. Nat. Med. 28, 2038–2044 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • International Classification of Violence against Children (United Nations Children’s Fund, 2023).

  • Kisely, S., Strathearn, L., Mills, R. & Najman, J. M. A comparison of the psychological outcomes of self-reported and agency-notified child abuse in a population-based birth cohort at 30-year-follow-up. J. Affect. Disord. 280, 167–172 (2021).

    Article 
    PubMed 

    Google Scholar 

  • Widom, C. S., DuMont, K. & Czaja, S. J. A prospective investigation of major depressive disorder and comorbidity in abused and neglected children grown up. Arch. Gen. Psychiatry 64, 49–56 (2007).

    Article 
    PubMed 

    Google Scholar 

  • Wise, L. A., Zierler, S., Krieger, N. & Harlow, B. L. Adult onset of major depressive disorder in relation to early life violent victimisation: a case–control study. Lancet 358, 881–887 (2001).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Chapman, D. P. et al. Adverse childhood experiences and the risk of depressive disorders in adulthood. J. Affect. Disord. 82, 217–225 (2004).

    Article 
    PubMed 

    Google Scholar 

  • Danese, A. & Widom, C. S. Associations between objective and subjective experiences of childhood maltreatment and the course of emotional disorders in adulthood. JAMA Psychiatry 80, 1009–1016 (2023).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Houtepen, L. C. et al. Associations of adverse childhood experiences with educational attainment and adolescent health and the role of family and socioeconomic factors: a prospective cohort study in the UK. PLoS Med. 17, e1003031 (2020).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Brown, J., Cohen, P., Johnson, J. G. & Smailes, E. M. Childhood abuse and neglect: specificity of effects on adolescent and young adult depression and suicidality. J. Am. Acad. Child Adolesc. Psychiatry 38, 1490–1496 (1999).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Comijs, H. C. et al. Childhood abuse in late-life depression. J. Affect. Disord. 147, 241–246 (2013).

    Article 
    PubMed 

    Google Scholar 

  • Xiang, X. & Wang, X. Childhood adversity and major depression in later life: a competing‐risks regression analysis. Int. J. Geriat. Psychiatry 36, 215–223 (2021).

    Article 

    Google Scholar 

  • Bhattarai, A. et al. Childhood adversity and mental health outcomes among university students: a longitudinal study. Can. J. Psychiatry 68, 510–520 (2023).

    Article 
    PubMed 

    Google Scholar 

  • Widom, C. S., Do, H. H., Lynch, K. S. & Manly, J. J. Childhood maltreatment and dementia risk factors in midlife: a prospective investigation. Curr. Alzheimer Res. 20, 636–647 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Xiao, Y. et al. Childhood maltreatment and depressive disorders in Chinese children and adolescents: a population-based case-control study. Asian J. Psychiatry 78, 103312 (2022).

    Article 

    Google Scholar 

  • ElBarazi, A. S. Childhood maltreatment and its mental health consequences among university’s students. Fam. J. (2023).

  • Gallo, E. A. G. et al. Childhood maltreatment preceding depressive disorder at age 18 years: a prospective Brazilian birth cohort study. J. Affect. Disord. 217, 218–224 (2017).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Andrews, B., Valentine, E. R. & Valentine, J. D. Depression and eating disorders following abuse in childhood in two generations of women. Br. J. Clin. Psychol. 34, 37–52 (1995).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Li, J. et al. Depressive symptoms mediate associations of adverse childhood experiences and chronic lung diseases: a mediation effect analysis. J. Affect. Disord. 345, 342–348 (2024).

    Article 
    PubMed 

    Google Scholar 

  • Fergusson, D. M., Boden, J. M. & Horwood, L. J. Exposure to childhood sexual and physical abuse and adjustment in early adulthood. Child Abuse Negl. 32, 607–619 (2008).

    Article 
    PubMed 

    Google Scholar 

  • Roustit, C. et al. Exposure to interparental violence and psychosocial maladjustment in the adult life course: advocacy for early prevention. J. Epidemiol. Commun. Health 63, 563–568 (2009).

    Article 
    CAS 

    Google Scholar 

  • Zhou, J. et al. Gender-specific associations between types of childhood maltreatment and major depressive disorder: a matched case–control study. Asia Pac. Psychiatry 15, e12538 (2023).

    Article 
    PubMed 

    Google Scholar 

  • Kang, W. et al. Gray and white matter abnormalities in major depressive disorder patients and its associations with childhood adversity. J. Affect. Disord. 330, 16–23 (2023).

    Article 
    PubMed 

    Google Scholar 

  • Hovens, J. G. F. M., Giltay, E. J., Spinhoven, P., Van Hemert, A. M. & Penninx, B. W. J. H. Impact of childhood life events and childhood trauma on the onset and recurrence of depressive and anxiety disorders. J. Clin. Psychiatry 76, 931–938 (2015).

    Article 
    PubMed 

    Google Scholar 

  • Ebert, D. D. et al. Prediction of major depressive disorder onset in college students. Depress. Anxiety 36, 294–304 (2019).

    Article 
    PubMed 

    Google Scholar 

  • Mullen, P. E., Martin, J. L., Anderson, J. C., Romans, S. E. & Herbison, G. P. The long-term impact of the physical, emotional, and sexual abuse of children: a community study. Child Abuse Negl. 20, 7–21 (1996).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Merza, K., Papp, G. & Kuritárné Szabó, I. The role of childhood traumatization in the development of borderline personality disorder in Hungary. Eur. J. Psychiatry 29, 105–118 (2015).

    Article 

    Google Scholar 

  • Su, Y. Y. et al. To what extent do social support and mastery mediate the association between childhood maltreatment and depression? A sequential causal mediation analysis. Epidemiol. Psychiatr. Sci. 31, e77 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Yu, P. et al. Variety ACEs and risk of developing anxiety, depression, or anxiety-depression co-morbidity: the 2006–2022 UK Biobank data. Front. Psychiatry 14, 1233981 (2023).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Broekhof, R., Nordahl, H. M., Tanum, L. & Selvik, S. G. Adverse childhood experiences and their association with substance use disorders in adulthood: a general population study (Young-HUNT). Addict. Behav. Rep. 17, 100488 (2023).

    PubMed 
    PubMed Central 

    Google Scholar 

  • Kascakova, N. et al. Associations of childhood trauma with long-term diseases and alcohol and nicotine use disorders in Czech and Slovak representative samples. BMC Public Health 22, 1769 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Telfar, S. et al. Child abuse and neglect and mental health outcomes in adulthood by ethnicity: findings from a 40-year longitudinal study in New Zealand/Aotearoa. Child Abuse Negl. 145, 106444 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Libby, A. M. et al. Childhood physical and sexual abuse and subsequent alcohol and drug use disorders in two American-Indian tribes. J. Stud. Alcohol 65, 74–83 (2004).

    Article 
    PubMed 

    Google Scholar 

  • Fenton, M. C. et al. Combined role of childhood maltreatment, family history, and gender in the risk for alcohol dependence. Psychol. Med. 43, 1045–1057 (2013).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Najman, J. M. et al. Do adversities experienced over the early life course predict mental illness and substance use behaviour in adulthood: a birth cohort study. J. Psychiatr. Res. 155, 542–549 (2022).

    Article 
    PubMed 

    Google Scholar 

  • Tanaka, M., Afifi, T. O., Wathen, C. N., Boyle, M. H. & MacMillan, H. L. Evaluation of sex differences in health-related quality of life outcomes associated with child abuse: results from the Ontario Child Health Study. Epidemiol. Psychiatr. Sci. 24, 353–363 (2015).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Rayworth, B. B., Wise, L. A. & Harlow, B. L. Childhood abuse and risk of eating disorders in women. Epidemiology 15, 271–278 (2004).

    Article 
    PubMed 

    Google Scholar 

  • Talmon, A. & Widom, C. S. Childhood maltreatment and eating disorders: a prospective investigation. Child Maltreat. 27, 88–99 (2022).

    Article 
    PubMed 

    Google Scholar 

  • Cohen, P., Brown, J. & Smailes, E. Child abuse and neglect and the development of mental disorders in the general population. Dev. Psychopathol. 13, 981–999 (2001).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Conroy, E., Degenhardt, L., Mattick, R. P. & Nelson, E. C. Child maltreatment as a risk factor for opioid dependence: comparison of family characteristics and type and severity of child maltreatment with a matched control group. Child Abuse Negl. 33, 343–352 (2009).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Scheidell, J. D. et al. Childhood traumatic experiences and the association with marijuana and cocaine use in adolescence through adulthood. Addiction 113, 44–56 (2018).

    Article 
    PubMed 

    Google Scholar 

  • Duncan, A. E. et al. The association between cannabis abuse and dependence and childhood physical and sexual abuse: evidence from an offspring of twins design. Addiction 103, 990–997 (2008).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Kisely, S., Strathearn, L. & Najman, J. The influence of child maltreatment on substance or alcohol use in 30-year-old adults: a birth cohort study. Drug Alcohol Rev. 40, 673–680 (2021).

    Article 
    PubMed 

    Google Scholar 

  • Huang, S. et al. The long-term effects of childhood maltreatment experiences on subsequent illicit drug use and drug-related problems in young adulthood. Addict. Behav. 36, 95–102 (2011).

    Article 
    PubMed 

    Google Scholar 

  • Akasaki, M. et al. Adverse childhood experiences and incident coronary heart disease: a counterfactual analysis in the Whitehall II prospective cohort study. Am. J. Prevent. Cardiol. 7, 100220 (2021).

    Article 

    Google Scholar 

  • Dong, M. et al. Insights into causal pathways for ischemic heart disease: adverse childhood experiences study. Circulation 110, 1761–1766 (2004).

    Article 
    PubMed 

    Google Scholar 

  • Monnat, S. M. & Chandler, R. F. Long-term physical health consequences of adverse childhood experiences. Sociol. Quart. 56, 723–752 (2015).

    Article 

    Google Scholar 

  • Fujiwara, T. & Kawakami, N. Association of childhood adversities with the first onset of mental disorders in Japan: results from the World Mental Health Japan, 2002–2004. J. Psychiatr. Res. 45, 481–487 (2011).

    Article 
    PubMed 

    Google Scholar 

  • Ten Have, M. et al. Childhood maltreatment, vulnerability characteristics and adult incident common mental disorders: 3-year longitudinal data among >10,000 adults in the general population. J. Psychiatr. Res. 113, 199–207 (2019).

    Article 
    PubMed 

    Google Scholar 

  • Widom, C. S. Posttraumatic stress disorder in abused and neglected children grown up. AJP 156, 1223–1229 (1999).

    Article 
    CAS 

    Google Scholar 

  • Raposo, S. M., Mackenzie, C. S., Henriksen, C. A. & Afifi, T. O. Time does not heal all wounds: older adults who experienced childhood adversities have higher odds of mood, anxiety, and personality disorders. Am. J. Geriat. Psychiatry 22, 1241–1250 (2014).

    Article 

    Google Scholar 

  • Rich-Edwards, J. W. et al. Abuse in childhood and adolescence as a predictor of type 2 diabetes in adult women. Am. J. Prevent. Med. 39, 529–536 (2010).

    Article 

    Google Scholar 

  • Lown, E. A. et al. Adverse childhood events and risk of diabetes onset in the 1979 National longitudinal survey of youth cohort. BMC Public Health 19, 1007 (2019).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Njoroge, A. et al. Assessment of adverse childhood experiences in the south bronx on the risk of developing chronic disease as adults. Cureus 15, e43078 (2023).

    PubMed 
    PubMed Central 

    Google Scholar 

  • Zhu, S. et al. Associations between adverse childhood experiences and diabetes among middle-aged and older Chinese: a social-ecological perspective. Epidemiol. Health 45, e2023071 (2023).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Shields, M. E. et al. Childhood maltreatment as a risk factor for diabetes: findings from a population-based survey of Canadian adults. BMC Public Health 16, 879 (2016).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Afifi, T. O., Mota, N., MacMillan, H. L. & Sareen, J. Harsh physical punishment in childhood and adult physical health. Pediatrics 132, e333–e340 (2013).

    Article 
    PubMed 

    Google Scholar 

  • Thomas, C., Hyppönen, E. & Power, C. Obesity and type 2 diabetes risk in midadult life: the role of childhood adversity. Pediatrics 121, e1240–e1249 (2008).

    Article 
    PubMed 

    Google Scholar 

  • Gaston, S. A. et al. Racial/ethnic differences in associations between traumatic childhood experiences and both metabolic syndrome prevalence and type 2 diabetes risk among a cohort of U.S. women. Diabetes Care 46, 341–350 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Duncan, A. E. et al. Relationship between abuse and neglect in childhood and diabetes in adulthood: differential effects by sex, national longitudinal study of adolescent health. Prev. Chronic Dis. 12, 140434 (2015).

    Article 

    Google Scholar 

  • Gelaye, B. et al. Childhood abuse, intimate partner violence and risk of migraine among pregnant women: an epidemiologic study. Headache 56, 976–986 (2016).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Karmakar, M., Elhai, J. D., Amialchuk, A. A. & Tietjen, G. E. Do personality traits mediate the relationship between childhood abuse and migraine? An exploration of the relationships in young adults using the Add Health dataset. Headache 58, 243–259 (2018).

    Article 
    PubMed 

    Google Scholar 

  • Brennenstuhl, S. & Fuller-Thomson, E. The painful legacy of childhood violence: migraine headaches among adult survivors of adverse childhood experiences. Headache 55, 973–983 (2015).

    Article 
    PubMed 

    Google Scholar 

  • Salzinger, S., Rosario, M., Feldman, R. S. & Ng-Mak, D. S. Adolescent suicidal behavior: associations with preadolescent physical abuse and selected risk and protective factors. J. Am. Acad. Child Adolesc. Psychiatry 46, 859–866 (2007).

    Article 
    PubMed 

    Google Scholar 

  • Calegaro, G. et al. Adverse childhood experiences (ACEs) and suicidal behaviors in emerging adulthood: the 1993 Pelotas birth cohort. Child Abuse Negl. 146, 106517 (2023).

    Article 
    PubMed 

    Google Scholar 

  • Thompson, M. P., Kingree, J. B. & Lamis, D. Associations of adverse childhood experiences and suicidal behaviors in adulthood in a U.S. nationally representative sample. Child Care Health Dev. 45, 121–128 (2019).

    Article 
    PubMed 

    Google Scholar 

  • Enns, M. W. et al. Childhood adversities and risk for suicidal ideation and attempts: a longitudinal population-based study. Psychol. Med. 36, 1769–1778 (2006).

    Article 
    PubMed 

    Google Scholar 

  • Bruffaerts, R. et al. Childhood adversities as risk factors for onset and persistence of suicidal behaviour. Br. J. Psychiatry 197, 20–27 (2010).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Johnson, J. G. et al. Childhood adversities, interpersonal difficulties, and risk for suicide attempts during late adolescence and early adulthood. Arch. Gen. Psychiatry 59, 741 (2002).

    Article 
    PubMed 

    Google Scholar 

  • Rajapakse, T. et al. Childhood adversity and self-poisoning: a hospital case control study in Sri Lanka. PLoS ONE 15, e0242437 (2020).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Fried, L. E., Williams, S., Cabral, H. & Hacker, K. Differences in risk factors for suicide attempts among 9th and 11th grade youth: a longitudinal perspective. J. Sch. Nurs. 29, 113–122 (2013).

    Article 
    PubMed 

    Google Scholar 

  • Archambault, É. et al. Mental illness following physical assault among children. JAMA Netw. Open 6, e2329172 (2023).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Russell, A. E. et al. Pathways between early‐life adversity and adolescent self‐harm: the mediating role of inflammation in the Avon Longitudinal Study of Parents and Children. Child Psychol. Psychiatry 60, 1094–1103 (2019).

    Article 

    Google Scholar 

  • Geng, S. et al. Risk factors and protective factors for nonsuicidal self-injury in adolescents: a hospital- and school-based case–control study. Clin. Child Psychol. Psychiatry 28, 1321–1332 (2023).

    Article 
    PubMed 

    Google Scholar 

  • Kisely, S., Strathearn, L. & Najman, J. M. Self-reported and agency-notified child abuse as contributors to suicidal behaviour in a population-based birth cohort study at 30-year-follow-up. Child Maltreat. 29, 155–164 (2024).

    Article 
    PubMed 

    Google Scholar 

  • Coogan, P. F. et al. Abuse during childhood and adolescence and risk of adult-onset asthma in African American women. J. Allergy Clin. Immunol. 131, 1058–1063 (2013).

    Article 
    PubMed 

    Google Scholar 

  • Han, Y.-Y., Yan, Q., Chen, W. & Celedón, J. C. Child maltreatment, anxiety and depression, and asthma among British adults in the UK Biobank. Eur. Respir. J. 60, 2103160 (2022).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Sun, Q. et al. Mediating role of depressive symptoms in the association between adverse childhood experiences and asthma. Child Abuse Negl. 149, 106662 (2024).

    Article 
    PubMed 

    Google Scholar 

  • Abajobir, A. A. et al. The association between substantiated childhood maltreatment, asthma and lung function: a prospective investigation. J. Psychosom. Res. 101, 58–65 (2017).

    Article 
    PubMed 

    Google Scholar 

  • Boynton-Jarrett, R., Rich-Edwards, J. W., Jun, H.-J., Hibert, E. N. & Wright, R. J. Abuse in childhood and risk of uterine leiomyoma: the role of emotional support in biologic resilience. Epidemiology 22, 6–14 (2011).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Harlow, B. L. & Stewart, E. G. Adult-onset vulvodynia in relation to childhood violence victimization. Am. J. Epidemiol. 161, 871–880 (2005).

    Article 
    PubMed 

    Google Scholar 

  • Ito, K., Doi, S., Isumi, A. & Fujiwara, T. Association between childhood maltreatment history and premenstrual syndrome. IJERPH 18, 781 (2021).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Harris, H. R. et al. Early life abuse and risk of endometriosis. Hum. Reprod. 33, 1657–1668 (2018).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Bertone-Johnson, E. R. et al. Early life emotional, physical, and sexual abuse and the development of premenstrual syndrome: a longitudinal study. J. Women’s Health 23, 729–739 (2014).

    Article 

    Google Scholar 

  • Liebermann, C. et al. Maltreatment during childhood: a risk factor for the development of endometriosis? Hum. Reprod. 33, 1449–1458 (2018).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Demakakos, P., Linara-Demakakou, E. & Mishra, G. D. Adverse childhood experiences are associated with increased risk of miscarriage in a national population-based cohort study in England. Hum. Reprod. 35, 1451–1460 (2020).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Kerkar, S., Shankar, A., Boynton-Jarrett, R. & Harville, E. W. Adverse childhood experiences are associated with miscarriage in adulthood: the GROWH study. Matern. Child Health J. 25, 479–486 (2021).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Abajobir, A. A., Kisely, S., Williams, G., Strathearn, L. & Najman, J. M. Risky sexual behaviors and pregnancy outcomes in young adulthood following substantiated childhood maltreatment: findings from a prospective birth cohort study. J. Sex Res. 55, 106–119 (2018).

    Article 
    PubMed 

    Google Scholar 

  • Trotta, G. et al. Cannabis use as a potential mediator between childhood adversity and first-episode psychosis: results from the EU-GEI case–control study. Psychol. Med. 53, 7375–7384 (2023).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Alkema, A. et al. Childhood abuse v. neglect and risk for major psychiatric disorders. Psychol. Med. 54, 1598–1609 (2024).

    Article 
    PubMed 

    Google Scholar 

  • Mansueto, G. & Faravelli, C. Stressful life events and psychosis: gender differences. Stress Health 38, 19–30 (2022).

    Article 
    PubMed 

    Google Scholar 

  • Chatziioannidis, S. et al. The role of attachment anxiety in the relationship between childhood trauma and schizophrenia-spectrum psychosis. Psychiatry Res. 276, 223–231 (2019).

    Article 
    PubMed 

    Google Scholar 

  • Widom, C. S., Czaja, S. J., Bentley, T. & Johnson, M. S. A prospective investigation of physical health outcomes in abused and neglected children: new findings from a 30-year follow-up. Am. J. Public Health 102, 1135–1144 (2012).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • London, S., Quinn, K., Scheidell, J. D., Frueh, B. C. & Khan, M. R. Adverse experiences in childhood and sexually transmitted infection risk from adolescence into adulthood. Sex. Trans. Dis. 44, 524–532 (2017).

    Article 

    Google Scholar 

  • Wilson, H. W. & Widom, C. S. Sexually transmitted diseases among adults who had been abused and neglected as children: a 30-year prospective study. Am. J. Public Health 99, S197–S203 (2009).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Goodwin, R. D. & Stein, M. B. Association between childhood trauma and physical disorders among adults in the United States. Psychol. Med. 34, 509–520 (2004).

    Article 
    PubMed 

    Google Scholar 

  • Campbell, J. A., Walker, R. J. & Egede, L. E. Associations between adverse childhood experiences, high-risk behaviors, and morbidity in adulthood. Am. J. Prev. Med. 50, 344–352 (2016).

    Article 
    PubMed 

    Google Scholar 

  • Harrington, M., Robinson, J., Bolton, S.-L., Sareen, J. & Bolton, J. A longitudinal study of risk factors for incident drug use in adults: findings from a representative sample of the US population. Can. J. Psychiatry 56, 686–695 (2011).

    Article 
    PubMed 

    Google Scholar 

  • Schwartz, A., Galera, C., Arsandaux, J., Montagni, I. & Tzourio, C. Adverse childhood experiences and illegal drug use among college students: findings from a French sample. Int. J. Behav. Med. (2024).

    Article 
    PubMed 

    Google Scholar 

  • Murphy, S., McElroy, E., Elklit, A., Shevlin, M. & Christoffersen, M. Child maltreatment and psychiatric outcomes in early adulthood. Child Abuse Rev. 29, 365–378 (2020).

    Article 

    Google Scholar 

  • Abajobir, A. A. et al. Childhood maltreatment and young adulthood hallucinations, delusional experiences, and psychosis: a longitudinal study. Schizophr. Bull. 43, 1045–1055 (2017).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Zhang, T., Kan, L., Jin, C. & Shi, W. Adverse childhood experiences and their impacts on subsequent depression and cognitive impairment in Chinese adults: a nationwide multi-center study. J. Affect. Disord. 323, 884–892 (2023).

    Article 
    PubMed 

    Google Scholar 

  • Vaeth, P. A. C., Ramisetty-Mikler, S. & Caetano, R. Depression among couples in the United States in the context of intimate partner violence. J. Interpers. Violence 25, 771–790 (2010).

    Article 
    PubMed 

    Google Scholar 

  • Soenke, M., Hahn, K. S., Tull, M. T. & Gratz, K. L. Exploring the relationship between childhood abuse and analogue generalized anxiety disorder: the mediating role of emotion dysregulation. Cogn. Ther. Res. 34, 401–412 (2010).

    Article 

    Google Scholar 

  • La Flair, L. N. et al. Childhood abuse and neglect and transitions in stages of alcohol involvement among women: a latent transition analysis approach. Drug Alcohol Depend. 132, 491–498 (2013).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • LeMasters, K. et al. Adverse childhood experiences and depression among women in rural Pakistan. BMC Public Health 21, 400 (2021).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Kisely, S., Strathearn, L. & Najman, J. M. Child maltreatment and mental health problems in 30-year-old adults: a birth cohort study. J. Psychiatr. Res. 129, 111–117 (2020).

    Article 
    PubMed 

    Google Scholar 

  • Young, R., Lennie, S. & Minnis, H. Children’s perceptions of parental emotional neglect and control and psychopathology. J. Child Psychol. Psychiatry 52, 889–897 (2011).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Abajobir, A. A. et al. Gender-based differences in injecting drug use by young adults who experienced maltreatment in childhood: findings from an Australian birth cohort study. Drug Alcohol Depend. 173, 163–169 (2017).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Kisely, S., Mills, R., Strathearn, L. & Najman, J. M. Does child maltreatment predict alcohol use disorders in young adulthood? A cohort study of linked notifications and survey data. Addiction 115, 61–68 (2020).

    Article 
    PubMed 

    Google Scholar 

  • Mall, S. et al. The relationship between childhood trauma and schizophrenia in the Genomics of Schizophrenia in the Xhosa people (SAX) study in South Africa. Psychol. Med. 50, 1570–1577 (2020).

    Article 
    PubMed 

    Google Scholar 

  • Haydon, A. A., Hussey, J. M. & Halpern, C. T. Childhood abuse and neglect and the risk of STDs in early adulthood. Perspect. Sex. Reprod. 43, 16–22 (2011).

    Article 

    Google Scholar 

  • Sanderson, M., Cook, M., Brown, L. L., Mallett, V. & Coker, A. L. Lifetime interpersonal violence or abuse and diabetes rates by sex and race. Am. J. Prev. Med. 65, 783–791 (2023).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Wegman, H. L. & Stetler, C. A meta-analytic review of the effects of childhood abuse on medical outcomes in adulthood. Psychosom. Med. 71, 805 (2009).

    Article 
    PubMed 

    Google Scholar 

  • Norman, R. E. et al. The long-term health consequences of child physical abuse, emotional abuse, and neglect: a systematic review and meta-analysis. PLoS Med. 9, e1001349 (2012).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Humphreys, K. L. et al. Child maltreatment and depression: a meta-analysis of studies using the Childhood Trauma Questionnaire. Child Abuse Negl. 102, 104361 (2020).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Gardner, M. J., Thomas, H. J. & Erskine, H. E. The association between five forms of child maltreatment and depressive and anxiety disorders: a systematic review and meta-analysis. Child Abuse Negl. 96, 104082 (2019).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • GBD 2019 Mental Disorders Collaborators. Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Psychiatry 9, 137–150 (2022).

  • Li, M. et al. The timing effect of childhood maltreatment in depression: a systematic review and meta-analysis. Trauma Violence Abuse 24, 2560–2580 (2023).

    Article 
    PubMed 

    Google Scholar 

  • Rakovski, C. et al. Childhood maltreatment as a predictor of substance use/misuse among youth: a systematic review and meta-analysis. Neurosci. Biobehav. Rev. 166, 105873 (2024).

    Article 
    PubMed 

    Google Scholar 

  • Guastaferro, K., Linden-Carmichael, A. N. & Chiang, S.-C. Association between child maltreatment and substance use disorder across emerging adulthood. Child Maltreat. 29, 340–349 (2024).

    Article 
    PubMed 

    Google Scholar 

  • Strøm, I. F., Birkeland, M. S., Aakvaag, H. F. & Thoresen, S. Trajectories of alcohol use and alcohol intoxication in young adults exposed to childhood violence and later problematic drinking behavior. J. Family Violence 36, 223–233 (2021).

    Article 

    Google Scholar 

  • Bensley, L. S., Van Eenwyk, J. & Simmons, K. W. Self-reported childhood sexual and physical abuse and adult HIV-risk behaviors and heavy drinking. Am. J. Prevent. Med. 18, 151–158 (2000).

    Article 
    CAS 

    Google Scholar 

  • GBD 2020 Alcohol Collaborators. Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020. Lancet 400, 185–235 (2022).

    Article 

    Google Scholar 

  • Karriker-Jaffe, K. J. et al. Can alcohol policy prevent harms to women and children from men’s alcohol consumption? An overview of existing literature and suggested ways forward. Int. J. Drug Policy 119, 104148 (2023).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Global Plan of Action to Strengthen the Role of the Health System within a National Multisectoral Response to Address Interpersonal Violence, in Particular against Women and Girls, and against Children (World Health Organization,2016).

  • Ghanem, N. The effect of violence in childhood on school success factors in US children. Child Abuse Negl. 120, 105217 (2021).

    Article 
    PubMed 

    Google Scholar 

  • Herrera, V. M. & McCloskey, L. A. Gender differences in the risk for delinquency among youth exposed to family violence. Child Abuse Negl. 25, 1037–1051 (2001).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Li, S., Zhao, F. & Yu, G. Childhood maltreatment and intimate partner violence victimization: a meta-analysis. Child Abuse Negl. 88, 212–224 (2019).

    Article 
    PubMed 

    Google Scholar 

  • Gil-González, D., Vives-Cases, C., Ruiz, M. T., Carrasco-Portiño, M. & Álvarez-Dardet, C. Childhood experiences of violence in perpetrators as a risk factor of intimate partner violence: a systematic review. J. Public Health 30, 14–22 (2008).

    Article 

    Google Scholar 

  • Curtis, A. et al. Childhood predictors of adult intimate partner violence perpetration and victimization. J. Fam. Violence 38, 1591–1606 (2023).

    Article 

    Google Scholar 

  • Carlson, C. et al. Violence against children and intimate partner violence against women: overlap and common contributing factors among caregiver-adolescent dyads. BMC Public Health 20, 124 (2020).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Clare, C. A. et al. Risk factors for male perpetration of intimate partner violence: a review. Aggress. Violent Behav. 56, 101532 (2021).

    Article 

    Google Scholar 

  • Colman, I. et al. Consistency in adult reporting of adverse childhood experiences. Psychol. Med. 46, 543–549 (2016).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Pinto, R. J. & Maia, Â. C. A comparison study between official records and self-reports of childhood adversity. Child Abuse Rev. 22, 354–366 (2013).

    Article 

    Google Scholar 

  • Farouki, L. et al. The global prevalence of female genital mutilation/cutting: a systematic review and meta-analysis of national, regional, facility, and school-based studies. PLoS Med. 19, e1004061 (2022).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Pourtaheri, A., Sany, S. B. T., Aghaee, M. A., Ahangari, H. & Peyman, N. Prevalence and factors associated with child marriage, a systematic review. BMC Women’s Health 23, 531 (2023).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Modecki, K. L., Minchin, J., Harbaugh, A. G., Guerra, N. G. & Runions, K. C. Bullying prevalence across contexts: a meta-analysis measuring cyber and traditional bullying. J. Adolesc. Health 55, 602–611 (2014).

    Article 
    PubMed 

    Google Scholar 

  • Ayenew, A. A., Mol, B. W., Bradford, B. & Abeje, G. Prevalence of female genital mutilation and associated factors among women and girls in Africa: a systematic review and meta-analysis. Syst. Rev. 13, 26 (2024).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Zhu, C., Huang, S., Evans, R. & Zhang, W. Cyberbullying among adolescents and children: a comprehensive review of the global situation, risk factors, and preventive measures. Front. Public Health 9, 634909 (2021).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Chandan, J. S. et al. The association between exposure to childhood maltreatment and the subsequent development of functional somatic and visceral pain syndromes. eClinicalMedicine 23, 100392 (2020).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Rehan, S. T. et al. Association of adverse childhood experiences with adulthood multiple sclerosis: a systematic review of observational studies. Brain Behav. 13, e3024 (2023).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Nash, K. et al. Association between childhood maltreatment and atopy in the UK: a population based retrospective cohort study. eClinicalMedicine 53, 101730 (2022).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Duan, P. et al. Impact of early life exposures on COPD in adulthood: a systematic review and meta-analysis. Respirology 26, 1131–1151 (2021).

    Article 
    PubMed 

    Google Scholar 

  • Higgins, D. J. & McCabe, M. P. Multiple forms of child abuse and neglect: adult retrospective reports. Aggress. Violent Behav. 6, 547–578 (2001).

    Article 

    Google Scholar 

  • Finkelhor, D., Ormrod, R. K. & Turner, H. A. Lifetime assessment of poly-victimization in a national sample of children and youth. Child Abuse Negl. 33, 403–411 (2009).

    Article 
    PubMed 

    Google Scholar 

  • Finkelhor, D., Ormrod, R. K. & Turner, H. A. Poly-victimization: a neglected component in child victimization. Child Abuse Negl. 31, 7–26 (2007).

    Article 
    PubMed 

    Google Scholar 

  • Baldwin, J. R. et al. A genetically informed Registered Report on adverse childhood experiences and mental health. Nat. Hum. Behav. 7, 269–290 (2023).

    Article 
    PubMed 

    Google Scholar 

  • Prom-Wormley, E. C., Ebejer, J., Dick, D. M. & Bowers, M. S. The genetic epidemiology of substance use disorder: a review. Drug Alcohol Depend. 180, 241–259 (2017).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • van Sprang, E. D. et al. Familial risk for depressive and anxiety disorders: associations with genetic, clinical, and psychosocial vulnerabilities. Psychol. Med. 52, 696–706 (2020).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Choenni, V., Hammink, A. & van de Mheen, D. Association between substance use and the perpetration of family violence in industrialized countries: a systematic review. Trauma Violence Abuse 18, 37–50 (2017).

    Article 
    PubMed 

    Google Scholar 

  • Guyatt, G. H. et al. GRADE guidelines: 4. Rating the quality of evidence—study limitations (risk of bias). J. Clin. Epidemiol. 64, 407–415 (2011).

    Article 
    PubMed 

    Google Scholar 

  • Dai, X. et al. Health effects associated with smoking: a Burden of Proof study. Nat. Med. 28, 2045–2055 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Flor, L. S. et al. Health effects associated with exposure to secondhand smoke: a Burden of Proof study. Nat. Med. (2024).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Gil, G. F. et al. Health effects associated with chewing tobacco: a Burden of Proof study. Nat. Commun. 15, 1082 (2024).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Razo, C. et al. Effects of elevated systolic blood pressure on ischemic heart disease: a Burden of Proof study. Nat. Med. 28, 2056–2065 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Lescinsky, H. et al. Health effects associated with consumption of unprocessed red meat: a Burden of Proof study. Nat. Med. 28, 2075–2082 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Stanaway, J. D. et al. Health effects associated with vegetable consumption: a Burden of Proof study. Nat. Med. 28, 2066–2074 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Page, M. J. et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372, n71 (2021).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Stevens, G. A. et al. Guidelines for accurate and transparent health estimates reporting: the GATHER statement. Lancet 388, e19–e23 (2016).

    Article 
    PubMed 

    Google Scholar 

  • Spencer, C. N. et al. Estimating the global health impact of gender-based violence and violence against children: a systematic review and meta-analysis protocol. BMJ Open 12, e061248 (2022).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Wei, Y. & Higgins, J. P. Estimating within‐study covariances in multivariate meta‐analysis with multiple outcomes. Stat. Med. 32, 1191–1205 (2013).

    Article 
    PubMed 

    Google Scholar 

  • Zheng, P., Barber, R., Sorensen, R. J. D., Murray, C. J. L. & Aravkin, A. Y. Trimmed constrained mixed effects models: formulations and algorithms. J. Comput. Graph. Stat. 30, 544–556 (2021).

    Article 

    Google Scholar 

  • Efron, B., Hastie, T., Johnstone, I. & Tibshirani, R. Least angle regression. Ann. Stat. 32, 407–499 (2004).

    Article 

    Google Scholar 

  • Tibshirani, R. Regression shrinkage and selection via the Lasso. J. R. Stat. Soc. Ser. B 58, 267–288 (1996).

    Article 

    Google Scholar 

  • Biggerstaff, B. J. & Tweedie, R. L. Incorporating variability in estimates of heterogeneity in the random effects model in meta-analysis. Stat. Med. 16, 753–768 (1997).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Egger, M., Smith, G. D., Schneider, M. & Minder, C. Bias in meta-analysis detected by a simple, graphical test. BMJ 315, 629–634 (1997).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

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